Dr. Muhammad Irfan-ur-Rehman Khan                  

Chairman/Associate Professor (TTS)
 DVM, M.Phil (UVAS), PhD (Uni. of Saskatchewan, Canada)

Phone: 92-42-99213659, Cell: 03330464308
Fax: 92-42-99211461
Email: irfan.khan@uvas.edu.pk

HEC Approved Supervisor

Biography

Dr. Irfan Khan graduated in 2003as Doctor of Veterinary Medicine from University of Veterinary and Animal Sciences (UVAS), Lahore. In 2006, he earned his M.Phil in the field of Theriogenology from UVAS. Dr. Irfan Khan worked as Veterinary Officer in Livestock and Dairy Development Department, Punjab in District Muzaffargarh for short time (January-April 2006) before joining the University of Veterinary and Animal Sciences Lahore in May 2006. He earned his PhD from University of Saskatchewan, Canada in 2014 under the Faculty Development Program of the HEC approved project: Establishment of Poultry and Dairy Animals Training and Research Centers, Pattoki, Kasur at UVAS.

Dr. Irfan has teaching expertise is in the area of reproductive science with speciality in ovarian physiology. Since 2006, he is involved in teaching undergraduate and postgraduate courses in Department of Theriogenology. During 2008 to 2013, he worked as research and teaching assistant at Department of Veterinary Biomedical Sciences, University of Saskatchewan, Saskatoon Canada and assisted faculty in teaching reproductive anatomy labs, delivered lectures on male reproductive anatomy and conducted biomedical rounds. As a lecturer and Associate Professor (Tenure Track System), Dr. Irfan has experience of performing obstetrics and gaeynolcolgical procedure in small and large ruminants and an expert in the in the field of veterinary ultrasonography. He has delivered lectures at national and international ultrasound training workshops. Dr. Irfan Khan has several publications in peer reviewed scientific journals and has participated in different international scientific meetings.

Area of Interest        

  • Ovarian Physiology
  • Follicular dynamics
  • Veterinary Reproductive Ultrasonography
  • Gene expression via Microarrays, RT-qPCR, and Immunohistochemistry
  • Oocyte competence in relation to ovulation time and heat stress
  • Markers of male puberty

Publication


 

 

  1. Hameed N, Akhter S, Souza-Fabjan, JMG, Zubair M, Khan MIR*. Effects of different extenders, storage temperatures, and antioxidant supplementation on chilled semen quality: a review. Tropical Animal Health Production 56, 85. https://doi.org/10.1007/s11250-024-03930-2
  2. Khan MT, Ahmad E, Husnain A, Yousaf MR, Oneeb M, Ahmad T, Khan MIR* Factors influencing pregnancy rate and loss after laparoscopic artificial insemination with frozen–thawed semen in Lohi sheep under sub-tropical conditions. Reproduction in Domestic Animals, Vol. 59 (5): https://doi.org/10.1111/rda.14579
  3. Hameed N, Zubair M, Ahmad N, Durrani AZ, Khan MIR*, Effect of cooling rate, extender type, and storage temperature on chilled sperm quality and pregnancy rate in Kail sheep. Small Ruminant Research, Vol. 231 https://doi.org/10.1016/j.smallrumres.2024.107202
  4. Khan MT, Khan M.I.R, Yasmin T, Khan GS and Riaz A. Effect of Ginseng on Blood Lipid Profile,Testosterone Level and Epididymal Sperm Quality of Aged BALB/C Mice. Pakistan Journal of Zoology, pp 1-7, 2024. https://dx.doi.org/10.17582/journal.pjz/20230323090320
  5. Sharif B, Hassan B, Arshad U, Tahir MZ, Ahmad E, Khan MIR, Shahzad M, Mohsin I, Sosa F, Rehman A. Effect of eCG dose on ovarian haemodynamics, hormonal profiles and prolificacy rate when oestrus was induced during low‐ breeding season in Beetal goats. Reproduction in Domestic Animals, Vol. 58 (1): 48-59, https://doi.org/10.1111/rda.14257
  6. Afzaal M, Khan MIR*, Ahmad W, Hayat A, Abbas Q, Arshad M, Hameed N, Mohsin I, Riaz A. Effects of prepartum melatonin treatment and suckling on postpartum reproductive performance of Beetal goats under subtropical conditions. Small Ruminant Research, Vol. 221, 106936 https://doi.org/10.1016/j.smallrumres.2023.106936
  7. Hameed N, Zubair M, Ahmad N, Durrani AZ, Khan MIR* Effects of extender type and storage time on sperm quality parameters of Kail ram semen stored at 5° C. Tropical Animal Health And Production, Vol. 55, 171 https://doi.org/10.1007/s11250-023-03594-4
  8. Khan MT, Ahmad E, Yousaf MR, Oneeb M, Khan MIR* Synergistic effect of extracellular adenosine triphosphate and quercetin on post-thaw quality and fertilization potential of Lohi ram sperm. Cryobiology, Vol. 113, 104593https://doi.org/10.1016/j.cryobiol.2023.104593
  9. Binyameen M, Khan MIR, Haque MNU, Tausif MA, Kok A, Van Knegse ATM, Tahir MZ. Effect of prepartum dietary energy sources on productive and reproductive performance in Nili Ravi buffaloes. Tropical Animal Health Production Vol. 55, 88. https://doi.org/10.1007/s11250-023-03510-w
  10. Shamsi IH, Suleman M, Shafique-ur-Rahman M, Hameed N, Atta A, Mohsin I, Yousaf MR, Channa, AI, Khan MIR*. Effect of Egg Yolk and Carboxylated Poly-l Lysine (CPLL) Supplementation to Tris-Citrate Extender on Post-Thaw Semen Quality of Beetal Male Goats. Pakistan Veterinary Journal 43(4): 671-676. http://dx.doi.org/10.29261/pakvetj/2023.099
  11. Sharif N, Ali A, Dawood M, Khan MIR, Do DN. Environmental Effects and Genetic Parameters for Growth Traits of Lohi Sheep. Animals. Vol. 12(24):3590. https://doi.org/10.3390/ani12243590
  12. Binyameen M, Khan MIuR, Ul Haque MN, Azam BE, Kok A, Van Knegsel ATM, Tahir MZ. Effect of Prepartum Dietary Energy Level on Production and Reproduction in Nili Ravi Buffaloes. Animals, Vol. 12(13):1683. https://doi.org/10.3390/ani12131683
  13. Hameed N, Khan MIR*, Zubair M, Andrabi SMH. Approaches of estrous synchronization in sheep: developments during the last two decades: a review Tropical Animal Health and Production, Vol. 53, 485, https://link.springer.com/arti cle/10.1007/s11250-021-02932-8
  14. Younis M, Khan MIR*, Abbas M, Murtaza A, Mohsin I, Shahzad M and Tahir MZ, Pattern of Ovarian Follicular Development and Steroid Hormone Concentrations during Estrous Cycle of Lohi Sheep. Pakistan Journal Zoology, 53: 987-993. https://dx.doi.org/10.17582/journal.pjz/20191104151133
  15. Ayaz M, Ahmed A, Khan MIR, Yousaf MS, Din BU, and Riaz A. Addition of Alpha-Lipoic Acid in Semen Extender Improves Post-Thaw Antioxidant Profile and Semen Quality of Achai (Bos Indicus) Cattle Bulls. JAPS: Journal of Animal & Plant Sciences, 31(3):650-656. https://doi.org/10.36899/JAPS.2021.3.0254
  16. Abbas M, Khan, MIR, Hameed N, Rehman A, Mohsin I, Bilal M, Shahzad M, Melatonin along with eCG improves fresh semen quality and plasma concentrations of melatonin and testosterone during non-breeding season in Beetal bucks. Small Ruminant Research, Vol 205,106569  https://doi.org/10.1016/j.smallrumres.2021.106569
  17. Yonis M, MIR Khan*, M Abbas, A Murtaza, M Shahzad and I Mohsin. Pattern of Ovarian Follicular Development and Steroid Hormone Concentrations during the Estrous Cycle in Lohi Sheep Pakistan Journal of Zoology 2020 (Manuscript ID: MH20191104151133), Accepted (since March 2020)
  18. Haq MEU, N Hameed, MIR Khan*, Q Abbas, T Sohail, A Rehman and I Mohsin. Temporal changes in physical signs of estrus and validation of fetal parameters for estimation of gestational stage through B-mode ultrasonography in Beetal goats. Pakistan Veterinary Journal, 2020 http://dx.doi.org/10.29261/pakvetj/2020.037
  19. Murtaza A, MIR Khan*, M Abbas, N Hameed, W Ahmad, I Mohsin and MZ Tahir. Optimal timing of artificial insemination and changes in vaginal mucous characteristics relative to the onset of standing estrus in Beetal goats. Animal Reproduction Science, 2020 Vol. 213:106249.
  20. Hameed, N., MIR Khan*, W Ahmad, M Abbas, A Murtaza, M Shahzad and N Ahmad. Follicular dynamics, estrous response and pregnancy rate following GnRH and progesterone priming with or without eCG during non- breeding season in anestrous Beetal goats. Small Ruminant Research, 2020 Vol.182(1):73-77
  21. A Murtaza, W Ahmad, T Sohail, MIR Khan*, I Mohsin, M Shahzad, M Hussain, MZ Tahir and M Ijaz. Follicular dynamics and changes in estradiol17β, progesterone and LH profiles following PGF2α induced estrus in early and late ovulating Beetal goats. Reproduction in Domestic Animals, 2019 54(3):545-550
  22. A Murtaza, MIR Khan*, W Ahmad, T Sohail, I Mohsin, M Shahzad, M Hussain, MZ Tahir and M Ijaz. Follicular Dynamics and Changes in Plasma Estradiol-17β and Progesterone Concentrations during Estrous Cycle in Beetal Goats. Pakistan Veterinary Journal, 2019 Vol. 39(2): 193-198
  23. Dias, FCF, MIR Khan, MA Sirard, GP Adams and J Singh. Transcriptome analysis of granulosa cells after conventional vs. long FSH-induced superstimulation in cattle. BMC genomics, 2018 Vol. 19(1):1-11
  24. Ahmed S, MIR Khan*, M Ahmad and S Iqbal. Effect of age on lipid peroxidation of fresh and frozen-thawed semen of Nili-Ravi buffalo bulls. Italian Journal of Animal Science, 2018 Vol. 17(3): 730-735
  25. Khan MIR*, ME Haq, A Rehman, I Mohsin, M Hassan, N Ahmad and R Kausar. Diagnosis of Ovarian Follicular Cyst in a Beetal Goat by Ultrasonography and Treatment with GnRH-PGF2α. Pakistan Veterinary Journal, 2017 Vol. 37(1): 120-122
  26. Khan MIR*, AA Channa and A Sattar. Diagnosis of Pseudopregnancy in a Beetal Goat using Real-time B-mode Ultrasonography. Pakistan Veterinary Journal, 2015 Vol. 35(4): 537-539
  27. Dias FCF, MIR Khan, GP Adams, MA Sirard, and J Singh. Granulosa cell function and oocyte competence: super-follicles, super-moms and super-stimulation in cattle. Animal Reproduction Science 2014 Vol. 149(1-2):80-89

 

Abstracts

  • Khan, M.I.R., Dias, F.C.F., Sirard, M.A., Adams, G.P, Singh, J. Effect of maternal age on the granulosa cell transcriptome of preovulatory follicles in cattle (41st Annual meeting of International Embryo Transfer Society (IETS), 10-13th January, 2015, Versailles, France, Reprod. Fertil. Dev. 25, Abstract no. 61075.
  • Singh, J., Dias, F.C.F., Khan, M.I.R., Adams, G.P., Sirard, M.A. Super Moms and Super Follicles: Granulosa cell function during aging. 4th Embryo Genomics Meeting, Hilton Quebec City, Canada, 9-11 October, 2013, pp. 13.
  • Khan, M.I.R., Dias, F.C.F., Dufort, I., Misra, V., Sirard, M.A., Singh, J. Selection of stable reference genes for relative gene expression analyses of bovine granulosa cells during maternal and follicular aging. 46th Annual meeting of Society for Study of Reproduction, (SSR), 22-26th July, 2013, Montreal, Quebec, Canada. Biology of Reproduction, 88: Abstract no. 655; p. 298.
  • Khan, M.I.R., Dias, F.C.F., Sirard, M.A., Adams, G.P., Singh, J. Transcriptome analysis of granulosa cells from growing dominant Follicle reveals age-associated changes at the time of follicle selection in aged beef cattle. 39th Annual meeting of International Embryo Transfer Society (IETS), 19-23th January, 2013, Hannover, Germany. Reprod. Fertil. Dev. 25, Abstract no. 2, pp.148.
  • Dias F.C.F., Khan M.I.R., Sirard M.A, Adams G.P, Singh J. Gene expression analysis of granulosa cells after ovarian super-stimulation treatment in cattle. 3rd Mammalian Embryo Genomics Meeting in Bonn, Germany, 20-22nd September, 2011, pp. 52.
  • Khan, M.I.R., Tahir M. Z., Nasser Z., Mushtaq M., Samad H.A., Singh J. Ahmad N. Effect of estradiol benzoate and GnRH on follicular wave emergence, estrus, ovulation and pregnancy rate in CIDR treated post-partum Nili-Ravi buffaloes. Society for Reproduction and Fertility, Conference and Exhibition, Edinburgh, 29th Jun-1st July, 2008. United Kingdom. pp. 48.
  • Ahmad, N., Khan, M.I.R., Rana, M. A. Ultrasonic monitoring of follicles and corpora lutea during synchronization and subsequent superovulation in summer anoestrous Nili-Ravi buffaloes. 38th Annual meeting of Society for Study of Reproduction, (SSR), 24-27th July, 2005, Quebec, Canada. Biology of Reproduction (Suppl. 1): Abstract no. W183.

 

 

Conferences/Meetings/Symposia/Workshops/Trainings (Attended)

  1. International Symposium on Dairy Animal Reproduction (ISDAR), 30-31st March 2015, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  2. 39th Annual Conference of International Embryo Transfer Society (IETS),19th-22nd  January, 2013, Hanover, Germany as finalist of “Student Competition” Abstract no.2
  3. 46th Annual meeting of Society for Study of Reproduction, (SSR), 22-26th July, 2013, Montreal, Quebec, Canada. Poster Competition, Abstract no. 655.
  4. Symposium on Functional Genomics of Early Development in Livestock, 24-26th July 2012, The Banff Center, Banff, Alberta, Canada.
  5. Reproductive Science and Medicine Research Symposium, 30th March 2012, University of Saskatchewan, Saskatoon, Canada.          
  6. Molecular Techniques related to Microarrays, July-August, 2009, EmbryoGene Network, University of Laval, Quebec, Canada.    
  7. EmbryoGene Network 1st Annual international Meeting and Research Symposium, July 2009, University of Laval, Quebec, Canada.
  8. Trainings on Laboratory Safety and WHMIS (Sep 2008), Biosafety Cabinet (Oct 2008), Biosafety (Oct 2008), and Radiation Safety (Nov 2008) organized by Department of Workplace Safety, Environment and Public Health, University of Saskatchewan, Saskatoon, Canada.  
  9. Experimental Animal User Training, College of Graduate Studies and Research, Dec 2008, University of Saskatchewan, Canada.    
  10. National Workshop on Cryopreservation of Bovine Semen, May, 12 -13, 2008, organized by University of Veterinary and Animal Sciences Lahore, Dairy Development Board, Islamabad, Directorate of Breed Improvement, L&DD, Punjab Pakistan, Agriculture and Agri-Food Canada, and Higher Education Commission of Pakistan.
  11. National Training Workshop on Equine Reproduction, 1-7 Feb, 2007,organized by University of Veterinary and Animal Sciences Lahore, Pakistan, University of Washington, Pullman, USA and Remount Veterinary and Farm Corps, Pakistan.
  12. Staff Development Training Workshop, 22nd Dec-22nd Jan, 2007, organized by Higher Education Commission of Pakistan and University of Veterinary & Animal Sciences Lahore, Pakistan.

Workshops/Trainings/Seminars (Organized)

  1. Presymposium Workshop on Bovine Reproductive Ultrasonography, 29th March 2015, Department of Theriogenology, University of Veterinary and Animal Sciences, Lahore.

Workshops/Trainings/Seminars (Resource Person)

  1. Resource Person: In Seminar on “Recent Trends in Buffalo Reproduction”, 30th May 2015, , Buffalo Research Institute (BRI), Pattoki, Kasur.
  2. Resource Persoon: In Presymposium Workshop on Bovine Reproductive Ultrasonography, 29th March 2015, Department of Theriogenology, University of Veterinary and Animal Sciences, Lahore.
  3. Demonstrator: In Workshop of Reproductive Ultrasonography in Domestic Animals, 14-18th April 2014, Department of Theriogenology, University of Veterinary and Animal sciences Lahore, Pakistan.
  4. Resource Person: In Reproductive Ultrasonography and Embryo Transfer Workshop, 1st-6th May 2010, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada.
  5. Resource Person: In Workshop on Application od Ultrasonography in Dairy Animals, 4th May 2008, University of Veterinary and Animal sciences Lahore, Pakistan and Nestle Pakistan