Dr. Imran Altaf

D.V.M (UAF), M.Sc. Hons. (UAF), Ph.D (UAF)
Assistant Professor(Tenure Track)

Tel: 92-42-99210256   Mobile: 0307-4464628
Email: imran.altaf@uvas.edu.pk

Biography

Dr. Imran Altaf is a Member of the University of Veterinary & Animal Sciences, Lahore where his work mainly focused on the development of novel biologics for the immunoprophylaxis of livestock and poultry. He not only work on the development and optimization of new microbiological testing methodologies to support the industrial sector of Pakistan but also focuses on promoting students academics and sharing knowledge about research. He also serves as member of activities related to accreditation of QOL according to ISO-17025. Dr. Imran altaf Prior to working at UVAS, has worked as manager production and technical advisor in different esteemed vaccine production unites. He is DVM, and MSc (Hons) from this esteemed Institute. Dr. Imran Altaf has a PhD Microbiology from UAF where he worked to initiate the trend of multivalent vaccines in livestock.  His research interests include investigative microbiology, advance cell culture techniques, vaccinology, isolation and molecular characterization of pathogens, immunology,  epidemiology, diagnosis, treatment, prevention and control of livestock & poultry disease. Currently he has optimized different toxicological laboratory assay for the mutagenic as well as genotoxic assessment of different environmental pollutants.

Areas of Interest

His areas of interest include:

  • Tissue / cell culture investigation
  • Vaccinology, Bacteriology and Immunological studies
  • Applied molecular biological techniques RT-PCR,PCR,DNA/RNA/Proteins Extraction and purifications, PAGE, Southern Blot, Western Blot, genotyping, primer design etc.
  • HPLC, GC, LC and HPTLC Expertise and Toxicological investigations

Publications


 

 

  1. Muhammad Sohaib, Muhammad Siddique Khushi Muhammad, Imran Altaf and Atif Hanif "Prevalence of avian influenza virus (H5) in poultry layer flocks in and around Faisalabad, Punjab-Pakistan" (2010) Pak. J. Zoology Vol:42(4) pp:000-000 (Journal) HEC Recognized: Yes
  2. Imran Altaf, M. Ashraf, M. Awais, Khushi Muhammad. “Efficacy of various Chemicals agents against Avian Influenza Virus (Type H9)” National Agriculture Research Centre, Agris Research, Universtity of Agriculture Faisalabad.
  3. K. Muhammad, M.A. Tariq, I. Altaf, M. Rabbani, R.M. Khawaja, Q. Akram, M.A. Ali and K. Hanif (2011). Effect of different adjuvants used in Foot and Mouth Disease Virus Vaccine on antibody response in buffalo calves. Accepted. Pakistan. J. Ani. Plant Sci., 11: 441.
  4. Zakir Ali, Azhar Maqbool, Khushi Muhammad, Imran Altaf, Muhammad Sarwar Khan, Masood Rabbani, Atif Hanif* and Hafiz Javed Iqbal "Antibody response of buffalo calves to montanide based Hyalomma Tick homogenate vaccine" (2009) Pak. J. Zoology Vol:Series No. 9 pp:167-172 (Journal) HEC Recognized: Yes
  5. Rashad Munir Khawaja, Khushi Muhammad, Waseem Shahzad, Irshad Hussain, Zafar Iqbal Choudhry, Farhat Nazir, Atia Bukhari, Imran Altaf and Atif Hanif "Isolation, adaptation and sero-typing of local strains of foot and mouth disease virus" (2009) Pak. J. Zoology Vol:Series No. 9 pp:173-177 (Journal) HEC Recognized: Yes
  6. K. Muuhammad, I. Altaf, A. Hanif, A. Anjum, and M. Y. Tipu “Monitoring of Hygienic status of raw milk marketed in Lahore city, Pakistan.” The journal of animal and plant sciences 19(2) : (2009), Page # 74-77
  7. Durre Shahwar, Sami Ullah, Imran Altaf, Naeem Ahmad, Saif Ullah, Muhammad Akmal Khan, Afifa Saeed “Evaluation of Antitumer, Antioxidant and antibacterial Activity of the Extract of Saussurea Atkinsonii” The Asian Journal of Chemistry, Vol. # 23 (11(2011), 5102-5106.
  8. Imran Altaf, M. Siddique, M. Arshad and M. Zargham “ Antibody Response of Rabbit to combined HS and FMD Virus Vaccine.”  Pak. Journal of plant and animal sciences. 2012: Vol 922)2 P.501-504.
  9. Lubna Shakir, Sohail Ejaz, M. Ashraf, Naureen Aziz Qureshi, M.A. Anjum, Imran Altaf, Aqeel Javaid “Ecotoxocological Resks associated with Tannery Effluent wastewater” Accepted in “Journal of envoriomental toxicology and pharmacology”  accepted date 24-11-2011, Ref. # ENVTOX 1536
  10. Khushi Muhammad, Zafar Iqbal Choudhary, Masood Rabbani, Imran Altaf, Munir Ahmad Tariq, M. Anees. “In process Quality Control factors Affecting Potency of FMD virus Vaccine”. Pak. J. of Zool, Vol. 43(2), Pp. 249-254,2011
  11. Faryal Gohar, M. Ashraf, Imran Altaf, Aqeel Javeed. “Cytotoxic and antiviral evaluation of ethanolic extract of three Opuntia Spp. Against Pest de petites Ruminants Virus” Submitted to “Journal of Animal and Plant Sciences”
  12. Ishrat Imran, M. Ashraf, Aqeel Javeed, and Imran Altaf. “In vitro antiviral activity of leaves of Azadirachta indica, Morigaoleifra and Morusalba against FMD virus’ Submitted to “Journal of animal and Plant Sciences”
  13. Rizwana Raheel, M. Ashraf, Aqeel Javeed and Imran Altaf. “A comparative study on antiviral and cytotoxic activity of different Parts of acacia Nilotica against PPR virus” Submitted to “Pakistan Veterinary Journal.”
  14. Misbah Afzal, M.Ashraf, Imran Altaf, Aqeel Javeed. “In vitro Evaluation of a antiviral and cytotoxic activity of Gingseng Root, Leaves of Tulsi and Aloe Vera against PPR virus. Submitted to “Journal of veterinary and animal Sciences.”
  15. Rizwana Raheel, M. Ashraf, Aqeel Javeed and Imran Altaf. “In vitro cytotoxic and antiviral activity of acacia Nolitica (L) Delil against PPR virus”. Submitted to “ “The Veterinary Journal.”

 

 

 

Training Attended

  • Uncertainty measurement in accordance with ISO/IEC 17025 standard Center for improvement and change management (Session: - June 2009)
  • Nuclear and other advance techniques an agriculture and biological research Nuclear instate for agriculture and biology (NIAB),FAISALABAD PAKISTAN. (Session: - Dec. 2007)
  • Short Training course on uncertainty of measurement in chemical and Microbiological testing
  • Assessor training course based on ISO/IEC 17025:2005 According to  APLAC TR001  by    Pakistan National Accreditation Council (PNAC) Session: - March 2009
  • Workshop on Pharmacokinetics  by the Society of Veterinary Pharmacology, College of veterinary sciences Lahore (University of veterinary and animal sciences Lahore Pakistan) Session: - June 2001RT-PCR for the diagnosis of FMD virus at University of veterinary and animal sciences Lahore Pakistan (Session: - June 2006)
  • Food and Feed security: Extraction and Quantification of AFLA toxins in feed at the University of veterinary and animal sciences Lahore Pakistan Session: - May 2007
  • Propagation of avian viruses in chicken Embryos at the University of veterinary and animal sciences Lahore Pakistan (Session: - June 2008)
  • Production and evaluation of bird flue vaccine at the University of veterinary and animal sciences Lahore Pakistan. ( Session:-June 2006)
  • International symposium on glycoprotein in health and diseases by the Pakistan academy of sciences School of biological sciences, University of Punjab Lahore Pakistan.  Institute of Molecular sciences and bioinformatics. (Session: - May 2008)
  • Production and quality control of Hemorrhagic Septicemia at the  National Agriculture Research center Islamabad Pakistan.( Session: - April 2003)
  • NIH web based training course “Protecting Human Research Participants” National institute of health USA  Date of completion  06-11-2008 Certificate No. 47244
  • Training course on “Genotyping” at the School of biological Sciences, university of Punjab Lahore, Pakistan Session: - 2010

Research Conducted:

  1. Isolation of Foot and Mouth disease virus on calf thyroid Primary cell line (PhD research, Prof. Dr. M. Siddique, Prof. Dr. M. Arshad, UAF).
  2. Molecular Characterization (RT-PCR) of Foot and Mouth disease virus (PhD research, Prof. Dr. M. Siddique, Prof. Dr. M. Arshad, UAF).
  3. Production and evaluation of inactivated oil based Foot and Mouth disease virus vaccine in vitro culture(PhD research, Prof. Dr. M. Siddique, Prof. Dr. M. Arshad, UAF).
  4.  Isolation, identification and biochemical characterization of pasteurella multocida
  5. Molecular characterization (PCR) of pasteurella multocida(PhD research, Prof. Dr. M. Siddique, Prof. Dr. M. Arshad, UAF).
  6. Typing of Foot and Mouth disease virus be Indirect sandwich ELISA(PhD research, Prof. Dr. M. Siddique, Prof. Dr. M. Arshad, UAF).
  7. Antibody titration of serum sample for the evaluation of Foot and mouth disease virus vaccine CFT(PhD research, Prof. Dr. M. Siddique, Prof. Dr. M. Arshad, UAF).
  8. Isolation and identification of Different Avian Influenza Viruses including H9, H7 and H5 (Prof. Dr. Khushi M, UVAS)
  9. Molecular characterization (RT-PCR) of Avian Influenza virus H7, H9 and H5(Prof. Dr. Khushi M, UVAS)
  10. Production and evaluation of inactivated oil based Avian Influenza virus (H7,H9 and H7+H9)vaccine(Prof. Dr. Khushi M, UVAS)
  11. Isolation and identification of New Castle disease virus (NDV) (Prof. Dr. Khushi M, UVAS)
  12. Molecular characterization (PCR) of ND virus(Prof. Dr. Khushi M, UVAS)
  13. Production and evaluation of inactivated oil based Avian Influenza virus (NDV, H9+ND) vaccine(Prof. Dr. Khushi M, UVAS)
  14. Antibacterial activity of ethanolic, chlorophormic and water extracted of different herbs against E.coli and Bacillus subtilis in vitro (Student M.Phill research. Prof. Dr. M Ashraf, UVAS)
  15.  Antibacterial activity of ethanolic, chlorophormic and water extracted of different herbs against E.coli and Bacillus subtilis in vitro(Student M.Phill research. Prof. Dr. M Ashraf, UVAS)
  16. Comparative Efficacy of  different chemical agents against Avian  Influenza Virus Type H9(Student M.Phill research. Prof. Dr. M Ashraf, UVAS)
  17. Microbiological analysis of commercial milk samples(Prof. Dr. Khushi M, UVAS)
  18. Somatic cell count in commercial milk samples((Dr. Atif Hanif, UVAS)
  19. Isolation and identification of theileria annulata from bovine blood samples((Dr. Atif Hanif, UVAS)
  20. Molecular characterization (PCR) of Theileria annulata((Dr. Atif Hanif, UVAS)
  21. Isolation and in vitro culture of lymphocytes (cell culture) ((Dr. Atif Hanif, UVAS)
  22. Adaptation and ropagation of theileria annulata on lymphocytes primary cell line((Dr. Atif Hanif, UVAS)
  23. Production and evaluation of attaneuated Theileria annulata live vaccine(Dr. Atif Hanif, UVAS)
  24. Evaluation of different paints used in surgical instrumental industry of Pakistan for their cytotoxic activity. (Prof. Dr. Khushi M, UVAS)
  25. Role of Biofermentor in the production of vaccines from aerobic (Pasteurella multocida) and anaerobic (Clostridium) vaccines(Prof. Dr. Khushi M, UVAS)
  26. Role of incu-drive in the production of Foot and Mouth disease inactivated vaccine(Prof. Dr. Khushi M, UVAS)
  27. Production of foot and mouth disease vaccine on cell suspension in a bioreactor/ fermentor ( Dr. Atif HanifM, UVAS)

Research Projects

  • As a Co-PI “Bioequivalence study of Pioglitazone and Metformin in healthy human (completed).
  • As a Co-PI “Bioequivalence study of Diclofenac potassium in healthy human”. (Completed).
  • As a Co-PI “Preparation of nasal spray of Ondansetron And pharmacokinetic comparison with tablets and injection”. (Completed)

Additional responsibilities:

  • Research  in Bioequivalence Study Center (BeSt), UVAS, Lahore.

Participation in various Conferences/Symposia

  • Attended the National Seminar and workshop on Environmental Toxicology and Health. 8th-9th March, 2011. Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences (UVAS), Lahore, Pakistan.
  • Participated and Presented Research Paper in 10th International & 22nd National Chemistry Conference, Department of Chemistry and Biochemistry, University of Agriculture, Faisalabad, Pakistan, 21st -23rd November, 2011.
  • Attended and presented a Research article in National Science Conference, PMAS-Arid Agriculture University Rawalpindi, January 10-12, 2012.