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Faculty of Veterinary Science

 
 
Department of Pathology

Introduction

The Department of Pathology fulfills essential role in teaching undergraduate and postgraduate students, along with disease diagnosis in poultry, pets, domestic and wild animals. Pathology provides the critical link between the basic and clinical sciences. The department isdedicated to disseminate the knowledge of diagnosis and control of diseases. Here we emphasize on understanding the pathological mechanisms of infectious diseases caused by bacteria, viruses, parasites and their vectors. Our dynamic faculty includes leading experts in host pathogen interaction, Molecular pathogenesis, Poultry Pathology, Diagnostic and Clinical Pathology.

Our vision is to provide leadership and excellence in disease diagnosis through innovative research and pioneering clinical activity. The outstanding facilities based in the department are second to none providing a range of world class diagnostic services, ensuring best practices and enabling us to provide better and faster results to the clients. The diagnostic services in the department are supported by the teachers, scientists, researchers and postgraduate students who have a vast experience of routine and more complicated clinical cases. We provide routine diagnostic techniques as well as specialized services in areas of hematology, serum biochemistry, cytology, histopathology, immunohistochemistry, endocrinology and postmortem examination. Our primary focus is animal welfare as well as providing the students hands on training and the clients a comprehensive diagnostic laboratory services. Our laboratory reports are accompanied by expert veterinary pathological advice and our pathologists are always available to discuss results or provide further advice according to the clients need. We strive to give same day service for in house tests on samples received during the normal working hours (hematology and serum biochemistry).

Being part of 24/7 extension services of UVAS, we are playing major role by conducting post mortem examination of dead animals at door step, collecting samples to diagnose the disease problem at earliest and giving technical services to treat and control disease problems.

Objectives

The Department of Pathology is focused on producing top quality students as well as professional pathologists for disease diagnosis both in livestock and poultry. The Department is striving to fulfill the following objectives:

  1. Produce highly trained manpower in the field of Pathology.
  2. Improve the quality of education as per needs of government and private sector.
  3. Plan strategies for accurate and early diagnosis of diseases.
  4. Conducting post graduate students research on current disease problems faced by livestock and poultry sector.
  5. Work for effective strategies to control the outbreaks.
  6. Conducting innovative research to develop new molecular techniques for emerging infections.
  7. Ensure the high standards of research work with internal and external quality control and assessments.
  8. Report the test results as soon as they are available by fax, email or by post.
  9. Liaise with other laboratories to provide broad spectrum of tests.
  10. Keep all record for reference and repeat reports if required at no extra cost.

Scope

The scope of Pathology is tremendous. Without an accurate diagnosis, the selection of a course of treatment for a sick animal may be limited. For companion animals, Pathology may mean analysis of blood or urine samples or even tissue biopsies of tumors. In the sphere of veterinary public health, it is vital that notifiable and other communicable diseases are diagnosed quickly and accurately. In research, the understanding of disease processes is important in the development of new treatments. In recent years, the study of the genome has opened a wide range of possibilities in investigating the causes of disease. And the areas of work include, but not limited to, animal diagnostics, teaching and research, pharmaceutical industry, wildlife and environmental conservation, government service, and army and defense. Private companies that produce drugs and insecticides employ pathologists.

Veterinary Pathology provides the reports of basic and applied research involving livestock and poultry. Our focus is to conduct the diagnostic investigations of diseases of animals especially of zoonotic nature. It provides a forum for the understanding of the pathological processes and evaluation of new and existing diagnostic applications of scientific advances and clinical pathologic correlations; fostering the acquisition and maintenance of up­to­date information to ensure high standards of practice; and, encouraging the publication of new information.

Staff Position

Chairman

Prof. Dr. Asim Aslam

Associate Professor

Dr. Muhammad Yasin Tipu

Assistant Professors

  1. Dr. Gulbeena Saleem
  2. Dr. Muti-ur-Rehman khan
  3. Dr. Raheela Akhtar
  4. Dr. Muhammad Saeed Imran

Lecturers

  1. Dr. Qamar Un Nisa
  2. Dr. Ishtiaq Ahmed (Ex-Pakistan Leave)

Invited Lectures

  • Dr. Raza Younis, An entrepreneur delivered a seminar on effect of hot weather in chickens.

HEC Approved Supervisors

  1. Prof. Dr. Asim Aslam
  2. Dr. Muhammad Yasin Tipu
  3. Dr. Gulbeena Saleem
  4. Dr. Muti-ur-Rehman khan
  5. Dr. Raheela Akhtar

Program and subject Course offered

  • Divide into DVM, MPhil and PhD

DVM/ Undergraduate Courses

Old Scheme of Studies

Course No

Title

Credit Hrs

TH    02302

General Veterinary  Pathology

4(3-1)

PATH    02402

Systemic Veterinary  Pathology

4(3-1)

PATH    02601

Meat Hygiene and Public Health

2(1-1)

PATH    02504

 Veterinary Clinical Pathology

2(0-2)

PATH    02901

Poultry Pathology

3(2-1)

PATH 02602

Forensic Medicine and Jurisprudence

1(1-0)

PATH 02503

Necropsy Practice

1(0-1)

PATH 05605

Clinical Pathology

3(1-2)

PATH 10405

General Pathology

3(2-1)

PATH 10505

Systemic Pathology

3(2-1)

New Scheme of Studies:

Course No

Title

Credit Hrs

PATH-02302

General Veterinary Pathology

3(2-1)

PATH-02402

Systemic Veterinary Pathology

3(2-1)

PATH-02504

Veterinary Clinical Pathology                                         

1(0-1)

PATH-02604

Poultry Pathology            

3(2-1)

PATH-02904

Meat Inspection and Necropsy Practice

3(2-1)

 

Activities of Dept. in Addition to Training & Research

  1. Postmortem examination of large, small animals and Poultry
  2. Hematology
  3. Blood Chemistry
  4. Serum analysis
  5. Histopathology
  6. Urinalysis
  7. Image analysis
  8. Fluorescent Microscopy
  9. PCR

Program/Subject Course Offered

Course No

Title

Credit Hrs

PATH    02302

General Veterinary  Pathology

4(3-1)

PATH    02402

Systemic Veterinary  Pathology

4(3-1)

PATH    02601

Meat Hygiene and Public Health

2(1-1)

PATH    02504

 Veterinary Clinical Pathology

2(0-2)

PATH    02901

Poultry Pathology

3(2-1)

PATH 02602

Forensic Medicine and Jurisprudence

1(1-0)

PATH 02503

Necropsy Practice

1(0-1)

PATH 05605

Clinical Pathology

3(1-2)

PATH 10505

General Pathology

3(2-1)

PATH 10405

Systemic Pathology

3(2-1)

Course No

Title

Credit Hrs

PATH    1001

Advanced General Pathology

4(3-1)

PATH    1002

Advanced Clinical Pathology

3(1-2)

PATH    1003

Necropsy Practice

2(0-2)

PATH    1004

Diagnostic Pathology

3(0-3)

PATH    1005

Oncology

3(2-1)

PATH    1006

Pathology of intoxications

3(3-1)

PATH    1007

Canine and Feline Pathology

3(2-1)

PATH    1008

Ruminants Pathology

4(3-1)

PATH    1009

Equine Pathology

3(2-1)

PATH    1010

Camel Pathology

3(2-1)

PATH    1011

Fish Pathology

3(2-1)

PATH    1012

Wildlife Pathology

3(2-1)

PATH    1013

Pathology of infectious diseases of Poultry

4(3-1)

PATH    1014

Pathology of non-infectious diseases of Poultry

3(2-1)

PATH    1015

Food Animal Pathology

3(2-1)

PATH    1016

Immunopathology

3(2-1)

PATH    1017

Molecular Pathobiology

3(2-1)

M. Phil Courses:

  • Advanced General Pathology
  • Advanced clinical Pathology
  • Necropsy practice
  • Canine and Feline Pathology
  • Pathology of infectious diseases of Poultry
  • Immunopathology
  • Molecular Pathology
  • Food Animal Pathology

PhD Courses:

  • Diagnostic Pathology
  • Oncology
  • Pathology of intoxications
  • Ruminants pathology
  • Equine Pathology
  • Camel Pathology
  • Fish Pathology
  • Wild life Pathology
  • Pathology of non-infectious diseases of Poultry

  Facilities

Principal Equipment

Salient Features/Services

    1. ELISA

    2. Molecular based diagnostic lab

    3. Automatic Tissue Processor, Cryostat, Auto staining unit

    4. Hematology Analyzer

    5. Chemistry Analyzer

    6. Image Analysis System

    7. Fluorescent Microscope

    8. pH meter, Spectrophotometer

    9. Advanced microscopes attached with cameras and multimedia

    10. Multi Head Microscope
       

    1. Polymerase Chain Reaction for Genetic analysis Bacterial, Viral, and Protozoan Parasites

    2. Histopathology, Automatic Tissue Processing

    3. Cryosectioning, Auto Staining

    4. Hematology

    5. Blood Chemistry Analysis

    6. Immunohistochemistry

    7. Fluorescent Microscopy for chromosomes and cells
      Other Routine Facilities:
      . Postmortem Examination
      . Routine Urine Analysis
      . Detection of Mycobacterium
      . Meat Inspection

Clinical Tests

Liver function Tests (LFT)

  • AST
  • ALT
  • ALP
  • Gamma GT
  • Total and direct bilirubin
  • Total Protein, Albumin

Kidney Funtion tests

  • Urea kinetic
  • Creatinine
  • Random and Fasting Sugar

Recent  Research Publications

  1. Arbab Sikandar, HafsaZaneb, Muhammad Younus, SaimaMasood, AsimAslam, Farina Khattak, Saima Ashraf, Muhammad ShahbazYousaf and HabibRehman (2017) Effect of sodium butyrate on performance, immune status, microarchitecture of small intestinal mucosa and lymphoid organs in broiler chickens. (Published) Asian-Australasian Journal of Animal Sciences. (IF: 0.75)
  2. Amir Rasool, Muti-ur-Rehman Khan, Muhammad Asad Ali, Aftab Ahmad Anjum, Ishtiaq Ahmed, AsimAslam, Ghulam Mustafa, SaimaMasood, Muhammad Amjad Ali and Muhammad Nawaz. Anti-avian influenza virus H9N2 activity of aqueous extracts ofZingiberofficinalis (Ginger) and Allium sativum (Garlic) in chick embryos. Pakistan journal of Pharmaceutical sciences (PJPS) Vol.30, No.4, July 2017, pp.1341-1344 Impact factor; 0.682. 
  3. ArbabSikandar, HafsaZaneb Muhammad Younus, SaimaMasood, AsimAslam, Saima Ashraf, Muhammad Adil and HabibRehman. Protective Effect of Sodium Butyrate on Growth Performance, Immune Responses and Gut Mucosal Morphometry in Salmonella-Challenged Broiler Chickens. Published in International Journal of Agriculture & Biology. ISSN Print: 1560–8530; ISSN Online: 1814–9596 17–0350/201x/00–0–000–000 DOI: 10.17957/IJAB/15.0424(IF: 0.93)
  4. B. Zahid1, A. Aslam ,Habib-ur-Rehman , J. I. Qazi , N. Ahmad , C. Ara , R. Akhtar  , and U. Bacha. Pathogenicity and immunosuppressive effect of different vaccines of infectious bursal disease virus. Published in The Journal of Animal & Plant Sciences, 27(4): 2017, Page: 1183-1189 ISSN: 1018-7081(IF: 0.422)
  5. S. Mahmood, M. Younus , A. Aslam , A. A. Anjum and M. L. Sohail. Chemical detoxification of afb1 in experimental quails using commercially available toxin binders. Published in The Journal of Animal & Plant Sciences 27(4): 2017, Page: 1133-1141 ISSN: 1018-7081. (IF: 0.422)
  6. S. Sarfaraz, K. Muhammad, T. Yaqub, A. Aslam, M. Rabbani, M. Khalil and R. Riaz. Antibody response of broilers to oil based combined avian influenza (h9 n2) and mycoplasma gallisepticum vaccine. Published in The Journal of Animal & Plant Sciences. 27(4): 2017, Page: 1150-1154 ISSN: 1018-7081(IF: 0.422).
  7. BeenishZahid, AsimAslam, Muhammad YasinTipu, TahirYaqub and Tariq Butt (2016). Conventional and Molecular Detection of Infectious Bursal Disease Virus in Broiler Chicken. Pakistan J. Zool., vol. 48(2), pp. 601-603. (IF: 0.478)
  8. RaheelaAkhtar, Iahtasham Khan,,Falk Melzer, Heinrich Neubauer,Aftab Ahmad Anjum, Muhammad Younus, AsimAslam, Sadaf Imran (2016). Differential anti-Brucella activity of bovine and murine macrophages. Indian Journal of Experimental Biology. 54: 452-456. (IF: 1.165)
  9. AzeemRiaz M, Aslam A, Rehman M, Yaqub T (2016). Pathological Investigation and Molecular Detection of Avian Pathogenic E.coliSerogroups in Broiler Birds. Journal of Veterinary Science and Technology. J.Vet. Sci..Technol 2016, 7:5 (IF: 0.75)
  10. T. Azeem, S.A. Abid, W. Ahmad, A. Aslam, M.L. Sohail, S. Jaleel and S. Umar (2016). Host Immune Responses and Vaccination against avian pathogenic Escherichia coli. World’s Poultry Science Journal. (IF: 1.8)
  11. BeenishZahid, AsimAslam. Immunological Responses of Broiler Vaccinated against various strains of Infectious Bursal Disease Virus. (2016) Published in The Journal of Animal and Plant Sciences. (IF: 0.448)
  12. S. A. Taseer, A. Aslam, Z. I. Chaudhary, K. Ashraf, R. Akhtar, G. Mustafa. (2016). The Effect of Omega 3 and Vitamin E against Avian Influenza in Broiler Chickens. Accepted in Hellenic Journal of Veterinary Medical Society. (IF 0.326)
  13. Nadia Mukhtar, TahirYaqub, Muhammad Munir, JawadNazir, AsimAslam, Amber Masood, ZarfashanTahir, Maryam Javed and AsifNadeem (2016). “Prevalence of Bovine Rota Virus in Calves, Punjab, Pakistan” Accepted in n the Journal of Animal and Plant Sciences, Volume: 27 (IF: 0.422).
  14. Liaqat, N. Arshad, G. Saleemand  M. Zain-ul-abIdeen (2017) Desulfovibrio vulgaris, biofilm formation and T3SS Inhibition BIOLOGIA, 63 (1), 115-123.
  15. M Younus, T Abbas, M Zafar, S Raza, A Khan, I Khan, M AIdrees, Q U Nisa, R Akhtar and G Saleem (2017). Quantification of enrofloxacin residues in broiler chicken tissues using competitive Enzyme-Linked Immunosorbent Assay. Indian Journal of Animal Sciences 87 (5): 123–00.
  16. SameeraAkhtar, Muhammad AkramMuneer, Khushi Muhammad, Muhammad YasinTipu, Muhammad Anees, Imran Rasheed, Raza-ur-Rehman and IrshadHussain (2017). Molecular Characterization and Epitope Mapping of Fusion (F) and Hemagglutinin (HN) Genes of Avian Paramyxovirus Serotype I from Peacocks in Pakistan. Pakistan J. Zool. 49(2): 755-759 (I.F.  0.478).
  17. Tufail H, Qureshi NA, Khan N, Iqbal KJ, Khan MR, and Maqbool A. 2017. Prevalence and effects of Lernaeacyprinacea (anchor worm) on the growth, skin histopathology and hematology of Catlacatla. Iranian Journal of Fisheries Sciences 16(1), 341-351. Impact factor= 0.285.
  18. R Akhtar, MN Anwar, I Khan, H El-Adawy, A Aslam, G Mustafa, SF Rehmani, MZ Saleem, SarwatNaz. 2017. Pathological Investigations of Organ Affinity of Brucella Species and their Cross Species Transmission. Pakistan Veterinary Journal. IF: 0.813.

2016

  • SameeraAkhtar; Muhammad AkramMunir; Khushi Muhammad; Muhammad YasinTipu; MasoodRabbani; Aziz ul-Rahman; Muhammad ZubairShabbir (2016). Genetic characterization and phylogeny of Pigeon Paramyxovirus isolate (PPMV-1) from Pakistan .Springerplus 5(1): 1295 (IF = 0.986)
  • Naveed Aslam, Muhammad Yasin Tipu, Muhammad Ishaq, Ann CowlingDavid McGill, Hassan Mahmood WarriachPeter Wynn (2016). Higher Levels of Aflatoxin M1 Contamination and Poorer Composition of Milk Supplied by Informal Milk Marketing Chains in Pakistan. Toxins (Basel) 8 (12): 347-358. (IF: 3.571)
  • F. Khattak, M. A. Shahzad, T. N. Pasha and G. Saleem (2016) Comparative evaluation of commercially available supplementary sources of inorganic phosphorous in broiler feed. The J. Anim. Plant Sci. 26(6): 2016 (Impact factor = 0.422)
  • K. Hassan, A.  Khalique, T. N. Pasha, M. Akram, S. Mahmood, A. W. Sahota, M. S. Imran and G. Saleem (2016) Influence of Moringaoleifera decorticated seed meal on broiler performance and immunity. Pakistan Veterinary Journal. ISSN: 0253-8318 (PRINT), 2074-7764 (ONLINE).
  • M. Younus, T. Abbas, M. Zafar, S. Raza, A. Khan, A.H. Saleem, M.A. Idrees, Q.U. Nisa, R. Akhtar and G. Saleem (2016) Assessment of heavy metal contamination in raw milk for human consumption.  South African Journal of Animal Science 2016, 46 (No. 2). (Impact factor = 0.504)
  • G. Saleem, R. Ramzaan, Farina Khattak, RaheelaAkhtar (2016). Effects of acetic acid supplementation in broiler chickens orally challenged with Salmonella Pullorum. Turkish Journal of Veterinary and Animal Sciences (In press). (Impact factor = 0.242)
  • Hameed S, Masood S, Zaneb H, Khan MS, Younis M, Avais M, and Khan MU. 2016. Dimensional characteristics of spermatozoa of Nili-Ravi buffalo bulls: seasonal and climatic influences. Turk J Vet AnimSci, 40(2), 207-213.(I.F.=0.449)
  •  Amir Rasool, Muti-ur-Rehman Khan, Muhammad Asad Ali, Aftab Ahmad Anjum, Ishtiaq Ahmed, AsimAslam, Ghulam Mustafa, SaimaMasood, Muhammad Nawaz. 2016 . Anti-avian influenza virus H9N2 activity of aqueous extracts from zingiberofficinalis (ginger) and allium sativum (garlic) on pathogenicity of on chicken embryos Pakistan Journal of pharmaceutical sciences. (Accepted)  MS No. 3932, (Impact Factor:0. 693)
  • SajidHameed, SaimaMasood, HafsaZaneb, Muhammad Sarwar Khan, Muhammad Younus, Habib UR Rehman, Muhammad Avais and MutiurRehman Khan. 2016 .Semen characteristics is influenced by seasonal and climatic variations in Nili-Ravi Buffalo Breeding Bulls. The Journal of Animal & Plant Sciences Volume: 26, No.5, Acceptance letter attached. No. 4803. (Impact Factor:0.422)
  • M. Younus, T. Abbas, M. Zafar,S. Raza, A. Khan, A.H. Saleem, M.A. Idrees, Q.U. Nisa, R. Akhtar& G. Saleem.2016. Assessment of heavy metal contamination in raw milk for human consumption. South African Journal of Animal Sciences. ISSN: 0375- 1589 (print) ISSN: 2221-4062 (online) 46(2): 1-4. IMPACT FACTOR:  0.504.
  • Muhammad Umair Khan, Saher Islam, AmnaArshadBajwa, Imran Rashid RaheelaAkhtar, Haroon Akbar, WasimShehzad and Muhammad Lateef. 2016. Optimization of single step multiplex PCR for detection of Eimeriatenella and Eimerianecatrix from commercial broilers. Indian Journal of Animal Sciences 86 (6): 671–672. IMACT FACTOR: 0.1.
  • RaheelaAkhtar, Iahtasham Khan,, Falk Melzer, Heinrich Neubauer, Aftab Ahmad Anjum, Muhammad Younus, AsimAslam, Sadaf Imran. 2016. Differential anti-Brucella activity of bovine and murine macrophages. Indian Journal of Experimental Biology. 54: 452-456.
  • F. Akhtar , M. Rabbani , K. Muhammad, M. Younus, A. A. Sheikh, R. Akhtar, J. Muhammad and A. Rasool. 2016. Phylogenetic grouping of the pathogenic E. Coli isolated from commercial broiler chicken in Pakistan. The Journal of Animal & Plant Sciences, 26(5): 1242-1246. IF 0.422.

Faculty Development

  • Mr.Ishtiaq Ahmad has gone abroad for Ph.D.
  • Prof. Dr. Asim Aslam attended a two days “ International Seminar on Poultry Diseases” at University of Agriculture Faisalabad on 14-15 December 2015.
  • Prof. Dr. Asim Aslam attended the training program on “leadership and change management” held from 27­30th April, 2015 at IBA Karachi under the tertiary education support program of HEC.
  • Prof. Dr. Asim Aslam attended a two days workshop on “Small ruminant value change (SRVC)” under agriculture innovation program funded by USAID on 11­ 12th May held in Islamabad, 2015.

Co-curricular Activities

  • Study tour of undergraduate students to Slaughter house to examine and learn gross lesions of various diseases.
  • Annual dinner of department of Pathology arranged at Salt n pepper , Lahore
  • Post –Graduate study tour to A.W. Chicks Hatchery and Farms in District Kasur.

Invited Lectures

  1. Prof. Dr. Ashiq Hussain Cheema demonstrated  histopathological slides of various disease conditions.
  2. Dr. Asif Latif Manager Big Feed gave presentation on modern practices in broiler farming in controlled shed rearing system.
  3. Dr. Muhammad Raza Younus Manager Hi-Tech Feed delivered lectures on Poultry industry modernization and disease control strategies in Pakistan

Measures taken to Enhance the Academics

    1. Up-gradation of Labs & Lecture rooms.
    2. Thirteen latest Olympus microscopes added in under graduate Lab.
    3. Addition of Chemistry and hematology Analyzer in Hematology Lab.
    4. Renovation of incineration facility in the Postmortem block.

  Induction of Modern Equipment

    1. Fluorescent Microscopy & Image Analysis System.
    2. Establishment of Molecular Pathology Laboratory
    3. Establishment of Poultry Diagnostic Laboratory in Postmortem Teaching Block

Other Activity

Department of Pathology in collaboration with Higher Education Commission has organized three day workshop on “Recent Advances in Necropsy Practice in Livestock  and Poultry and its Vetro-Legal Implications” held on 25 to 27 Feb, 2015 at Conference Hall, UVAS, Lahore.

Research Priorities

  1. Development of advanced molecular diagnostic techniques for various infectious diseases
  2. Pathology and pathogenesis of various diseases of zoonotic importance
  3. Understanding the pathological mechanisms of infectious diseases caused by bacteria, viruses, parasites, and their vectors
  4. Developing novel approaches in the research of host-pathogen interaction and exploring its molecular pathogenesis for various infectious diseases.
  5. Studies on pathological effects of drugs/heavy metals/indigenous plants/ fungal toxins in animals and poultry
  6. Pathology and pathogenesis of infectious and non-infectious diseases of poultry
  7. Building bridge between basic research and in vivo application using animal models

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Prof. Dr. Asim Aslam