Department of Pathology

Introduction

The Department of Pathology fulfills essential role in teaching undergraduate and postgraduate students, along with disease diagnosis in poultry, pets, domestic and wild animals. Pathology provides the critical link between the basic and clinical sciences. The department isdedicated to disseminate the knowledge of diagnosis and control of diseases. Here we emphasize on understanding the pathological mechanisms of infectious diseases caused by bacteria, viruses, parasites and their vectors. Our dynamic faculty includes leading experts in host pathogen interaction, Molecular pathogenesis, Poultry Pathology, Diagnostic and Clinical Pathology.

Our vision is to provide leadership and excellence in disease diagnosis through innovative research and pioneering clinical activity. The outstanding facilities based in the department are second to none providing a range of world class diagnostic services, ensuring best practices and enabling us to provide better and faster results to the clients. The diagnostic services in the department are supported by the teachers, scientists, researchers and postgraduate students who have a vast experience of routine and more complicated clinical cases. We provide routine diagnostic techniques as well as specialized services in areas of hematology, serum biochemistry, cytology, histopathology, immunohistochemistry, endocrinology and postmortem examination. Our primary focus is animal welfare as well as providing the students hands on training and the clients a comprehensive diagnostic laboratory services. Our laboratory reports are accompanied by expert veterinary pathological advice and our pathologists are always available to discuss results or provide further advice according to the clients need. We strive to give same day service for in house tests on samples received during the normal working hours (hematology and serum biochemistry).

Being part of 24/7 extension services of UVAS, we are playing major role by conducting post mortem examination of dead animals at door step, collecting samples to diagnose the disease problem at earliest and giving technical services to treat and control disease problems.

Objectives

The Department of Pathology is focused on producing top quality students as well as professional pathologists for disease diagnosis both in livestock and poultry. The Department is striving to fulfill the following objectives:

  1. Produce highly trained manpower in the field of Pathology.
  2. Improve the quality of education as per needs of government and private sector.
  3. Plan strategies for accurate and early diagnosis of diseases.
  4. Conducting post graduate students research on current disease problems faced by livestock and poultry sector.
  5. Work for effective strategies to control the outbreaks.
  6. Conducting innovative research to develop new molecular techniques for emerging infections.
  7. Ensure the high standards of research work with internal and external quality control and assessments.
  8. Report the test results as soon as they are available by fax, email or by post.
  9. Liaise with other laboratories to provide broad spectrum of tests.
  10. Keep all record for reference and repeat reports if required at no extra cost.

Scope

The scope of Pathology is tremendous. Without an accurate diagnosis, the selection of a course of treatment for a sick animal may be limited. For companion animals, Pathology may mean analysis of blood or urine samples or even tissue biopsies of tumors. In the sphere of veterinary public health, it is vital that notifiable and other communicable diseases are diagnosed quickly and accurately. In research, the understanding of disease processes is important in the development of new treatments. In recent years, the study of the genome has opened a wide range of possibilities in investigating the causes of disease. And the areas of work include, but not limited to, animal diagnostics, teaching and research, pharmaceutical industry, wildlife and environmental conservation, government service, and army and defense. Private companies that produce drugs and insecticides employ pathologists.

Veterinary Pathology provides the reports of basic and applied research involving livestock and poultry. Our focus is to conduct the diagnostic investigations of diseases of animals especially of zoonotic nature. It provides a forum for the understanding of the pathological processes and evaluation of new and existing diagnostic applications of scientific advances and clinical pathologic correlations; fostering the acquisition and maintenance of up­to­date information to ensure high standards of practice; and, encouraging the publication of new information.

Staff Position

Chairman

Professors

  1. Prof. Dr. Asim Aslam
  2. Prof. Dr. Muhammad Yasin Tipu

Associate Professor

  1. Dr. Gulbeena Saleem
  2. Dr. Muti-ur-Rehman khan
  3. Dr. Raheela Akhtar

Assistant Professors

  1. Dr. Muhammad Saeed Imran
  2. Dr. Qamar Un Nisa

Lecturers

  1. Mr. Adeem Rehman Raffie
  2. Mr. Ghulam Mustafa

HEC Approved Supervisors

  1. Prof. Dr. Asim Aslam
  2. Dr. Muhammad Yasin Tipu
  3. Dr. Gulbeena Saleem
  4. Dr. Muti-ur-Rehman khan
  5. Dr. Raheela Akhtar

Program and subject Course offered

  • Divide into DVM, MPhil and PhD

DVM/ Undergraduate Courses

Old Scheme of Studies

Course No

Title

Credit Hrs

PATH    02302

General Veterinary  Pathology

3(2-1)

PATH    02402

Systemic Veterinary  Pathology

3(2-1)

PATH    02904

Meat inspection and necropsy practice

3(2-1)

PATH    02504

 Veterinary Clinical Pathology

1(0-1)

PATH    02604

Poultry Pathology

3(2-1)

PATH 05605

Clinical Pathology

3(1-2)

PATH 10405

General Pathology

3(2-1)

PATH 10505

Systemic Pathology

3(2-1)

PATH 26301

General Pathology

3(2-1)

PATH 26505

Blood Disorders

3(2-1)

PATH 26304

Hematology 1

3(2-1)

New Scheme of Studies:

Course No

Title

Credit Hrs

PATH-02302

General Veterinary Pathology

3(2-1)

PATH-02402

Systemic Veterinary Pathology

3(2-1)

PATH-02504

Veterinary Clinical Pathology                                         

1(0-1)

PATH-02604

Poultry Pathology            

3(2-1)

PATH-02904

Meat Inspection and Necropsy Practice

3(2-1)

 

Activities of Dept. in Addition to Training & Research

  1. Postmortem examination of large, small animals and Poultry
  2. Hematology
  3. Blood Chemistry
  4. Serum analysis
  5. Histopathology
  6. Fine needle aspiration cytology
  7. Urinalysis
  8. Image analysis
  9. Fluorescent Microscopy
  10. PCR

Program/Subject Course Offered

Course No

Title

Credit Hrs

PATH    02302

General Veterinary  Pathology

4(3-1)

PATH    02402

Systemic Veterinary  Pathology

4(3-1)

PATH    02601

Meat Hygiene and Public Health

2(1-1)

PATH    02504

 Veterinary Clinical Pathology

2(0-2)

PATH    02901

Poultry Pathology

3(2-1)

PATH 02602

Forensic Medicine and Jurisprudence

1(1-0)

PATH 02503

Necropsy Practice

1(0-1)

PATH 05605

Clinical Pathology

3(1-2)

PATH 10505

General Pathology

3(2-1)

PATH 10405

Systemic Pathology

3(2-1)

Course No

Title

Credit Hrs

PATH    1001

Advanced General Pathology

4(3-1)

PATH    1002

Advanced Clinical Pathology

3(1-2)

PATH    1003

Necropsy Practice

2(0-2)

PATH    1004

Diagnostic Pathology

3(0-3)

PATH    1005

Oncology

3(2-1)

PATH    1006

Pathology of intoxications

3(3-1)

PATH    1007

Canine and Feline Pathology

3(2-1)

PATH    1008

Ruminants Pathology

4(3-1)

PATH    1009

Equine Pathology

3(2-1)

PATH    1010

Camel Pathology

3(2-1)

PATH    1011

Fish Pathology

3(2-1)

PATH    1012

Wildlife Pathology

3(2-1)

PATH    1013

Pathology of infectious diseases of Poultry

4(3-1)

PATH    1014

Pathology of non-infectious diseases of Poultry

3(2-1)

PATH    1015

Food Animal Pathology

3(2-1)

PATH    1016

Immunopathology

3(2-1)

PATH    1017

Molecular Pathobiology

3(2-1)

M. Phil Courses:

  • Advanced General Pathology
  • Advanced clinical Pathology
  • Necropsy practice
  • Canine and Feline Pathology
  • Pathology of infectious diseases of Poultry
  • Immunopathology
  • Molecular Pathology
  • Food Animal Pathology

PhD Courses:

  • Diagnostic Pathology
  • Oncology
  • Pathology of intoxications
  • Ruminants pathology
  • Equine Pathology
  • Camel Pathology
  • Fish Pathology
  • Wild life Pathology
  • Pathology of non-infectious diseases of Poultry

  Facilities

Principal Equipment

Salient Features/Services

    1. ELISA

    2. Molecular based diagnostic lab

    3. Automatic Tissue Processor, Cryostat, Auto staining unit

    4. Hematology Analyzer

    5. Chemistry Analyzer

    6. Image Analysis System

    7. Fluorescent Microscope

    8. pH meter, Spectrophotometer

    9. Advanced microscopes attached with cameras and multimedia

    10. Multi Head Microscope
       

    1. Polymerase Chain Reaction for Genetic analysis Bacterial, Viral, and Protozoan Parasites

    2. Histopathology, Automatic Tissue Processing

    3. Cryosectioning, Auto Staining

    4. Hematology

    5. Blood Chemistry Analysis

    6. Immunohistochemistry

    7. Fluorescent Microscopy for chromosomes and cells
      Other Routine Facilities:
      . Postmortem Examination
      . Routine Urine Analysis
      . Detection of Mycobacterium
      . Meat Inspection

Clinical Tests

Liver function Tests (LFT)

  • AST
  • ALT
  • ALP
  • Gamma GT
  • Total and direct bilirubin
  • Total Protein, Albumin

Kidney Funtion tests

  • Urea kinetic
  • Creatinine
  • Random and Fasting Sugar

Recent  Research Publications

PUBLICATIONS IN SCIENTIFIC JOURNAL, HEC APPROVED/ IMPACT FACTOR

Sr. No.

Title (Complete reference)

Impact factor

  1.  

Raheem MA, Xue M, Ahmad HI, Ahmad MZ, Tipu MY, Afzal G, SongX, Rahim MA, Qi K, Adaptation to host-specific bacterial pathogens drive rapid evolution of novelPhoP/PhoQ regulation pathway modulating the virulence, Microbial Pathogenesis (2020), doi: https://doi.org/10.1016/j.micpath.2020.10399.

2.914

  1.  

Shahid, M.F., Yaqub, T., Tipu, M.Y., Aslam, A., Yaqub, S., Rahman, A. and Ali, M. 2019. Comparative pathogenic potential of avian influenza A/ H9N2 viruses isolated from commercial, backyard and fancy birds. Punjab Univ. J. Zool., 34(2): 143-148. https://dx.doi.org/10.17582/journal.pujz/2019.34.2.143.148

Under calculation

3

In-vitro efficacy of Arachis hypogaea (Peanut) peels extract against Haemonchus contortus Published in journal of Hellenic Journal of Veterinary Medical society

0.327

4

G. Mustafa, A. AslamM.Y. Tipu, S. Masood, U. Iqbal, A. Mahmood,
M. Tayyab and  I. Irshad. Title: Efficacy evaluation of commercial vaccines against circulating filed isolates of avian influenza h9n2 and infectious bronchitis viruses in broilers. Journal of biological regulators and homeostatic agents (Accepted vide letter no. JBR 19-497)

 

1.505

5


Sharaf S, Khan MUR, Aslam A and Rabbani M, 2020. Toxico-pathological effects of heavy metals from industrial drainage waste water on vital organs of small ruminants in Lahore. Environmental Science and Pollution Research Ms.No. ESPR-D-20-00234R2 Accepted in Environmental Science and Pollution Research Journal.

03.056

6

Nadeem, S.M., Khan, M.ur.R., Aslam, A.,Sheikh, A.A., Ahmad, A., Latif, A.A. and Anjum, A. (2020). Clinico-Pathological and Hemato-Biochemical Assessment of Field Originated Chicken Anemia Virus in Experimentally Challenged Broiler Chicken. Indian Journal of Animal Research. Submitted: 23-11-2019 Accepted: 02-05-2020 Published:

0.395

7

Syed Maaz Nadeem, Muti ur Rehman Khan, Asim Aslam, Ali Ahmad Sheikh, Arfan Ahmad and Muhammad Anees. 2020 Cytological changes in Chicken Infectious Anemia Virus infected bone marrow in broilers. Manuscript ID MH20191120171141-R1 Accepted in Pakistan J. Zool.

0.790

8

Syed Maaz Nadeem, Muti ur Rehman Khan, Asim Aslam, Ali Ahmad Sheikh, Arfan Ahmad and Muhammad Anees. 2020. Molecular Characterization and Phylogeny of Chicken Anemia Virus Detected in Broiler Poultry Flocks in Punjab, Pakistan. Pakistan J. Zool., vol. 52(1), pp 1-4, 2020. DOI: https://dx.doi.org/10.17582/journal.pjz/2020.52.1.sc14.

0.790

9

Hussain, A., Wu, T., Li, H., Fan, L., Li, K., Gao, L., Wang, Y., Gao, Y., Liu, C., Cui, H., Pan, Q., Zhang, Y., Aslam, A. and Khan, MUR. 2019. Pathogenic Characterization and Full Length Genome Sequence of a Reassortant Infectious Bursal Disease Virus Newly Isolated in Pakistan. Virologica Sinica34(1), pp.102-105.

2.467

10

Abdullah, S.W., Khan, M.U.R., Aslam, A., Masood, S., Bajwa, A.G.  and Sheikh, A.A.  (2020).  Detection  of Bovine Ephemeral  Fever Virus and Its Effects on Blood Parameters and  Serum  Calcium  Levels  in  Cattle  Population  of  District  Swabi, Pakistan,  Indian  Journal  of  Animal  Research,  54(): Submitted: 10-07-2019   Accepted:06-12-2019  Indian Journal of Animal Research DOI: 10.18805/ijar.B-1019

0.395

11

Sharaf S, Khan MUR, Aslam A and Rabbani M, 2019. Comparative study of heavy metals residues and histopathological alterations in large ruminants from selected areas around industrial waste drain. Pak Vet J. http://dx.doi.org/10.29261/pakvetj/2019.111.

1.360

12

Nisa Q, Younis M, Khan MR, Maqbool A, Khan I, Sohail ML, Umar S. 2019. Mycoplasma gallisepticum modifies virus shedding and immune response of Newcastle disease virus in broilers. Indian Journal of Animal Research.(53):932-937 DOI. 10.18805/ijar.B-769 

0.395

13

Saleem, M.U., Masood, S., Zaneb, H., Durrani, A.Z., Aslam, A., Ashraf, K., Khan, M.U.R., Usman, M.M. and Qaisar, S., 2019. Combined supplementation of organic acid blend and mannanoligosaccharide suppresses expression of heat shock protein 70 in broilers. Indian Journal of Animal Research53(3).

0.395

14

Rasool A, Anjum A,  Rabbani M,  Lateef M, Nawaz M,  Akhtar F, Kanwal K, Sattar S. 2017. Preparation of Mycoplasma Synoviae Antigens and evaluations by Rapid Single Agglutination and Enzyme Linked Imunnosorbent Assay. Journal of Animal & Plant Science. 27(3): 841-847..

0.407

RESEARCH PROJECTS

ON-GOING FOREIGN FUNDED RESEARCH PROJECTS DURING (2018-19)


Sr. No.

Project Title

Cost (Million PKR)

Funding Agency

Principal Investigator

1

Evaluation of Aldecoc against Amelioration of Farm Surface Contamination by Eimeria Oocysts leading to Enhanced Coccidiostat Efficacy by Ewabo Essential Oils in Broilers.

2540 EUR

Ewabo Chemikalien GmbH (Germany)

Prof. Dr. Asim Aslam

2

Study on Avian major infectious disease prevention and control and development of international scientific and technological cooperation platform

0.84 million Yuan (RMB)

Ministry of Science and Technology China 

Prof. Dr. Asim Aslam & Dr. Muti-ur-Rehman

ON-GOING LOCAL FUNDED RESEARCH PROJECTS DURING (2018-19)


Sr. No.

Project Title

Cost (Million PKR)

Funding Agency

Principal Investigator

1

Prevalence, Molecular Characterization and Control of Contagious bovine Pleuropneumonia in Domestic Ruminants of Punjab

1.88 Million

HEC

Prof. Dr. Asim Aslam

2

Project Carrier Potential of resident wild birds on Newcastle DV and AI (H9) Viruses in Central Punjab

0.82 million

HEC

Prof. Dr. Asim Aslam

3

Pathological Studies on Toxoplasmosis in Food Animals in Khyber Pakhtunkhwa Pakistan

2.720 million PKR.

HEC

Dr. M. Yasin Tipu

4

“Use of indigenous fruit extracts as nutraceuticals and their therapeutic efficacy against Clostridium perfringens in broiler chickens

3.11

Pakistan Science Foundation

Dr. Gulbeena Saleem

5

Genetic Diversity among Marek’s Disease Field and Vaccine Viruses to Improve Prophylaxis

3.014 Million           

NRPU, HEC

Dr. Muti ur Rehman Khan

6

One Health Approach for Molecular Diagnosis, Epidemiology and control of brucellosis in Pakistan UVAS, Lahore

3.60 million

ALP

Dr. Raheela Akhtar

7

Development, validation and commercialization of rapid screening diagnostic strip for cutaneously transmitted bovine zoonosis in Pakistan: A step towards control of occupational hazards in dairy industry

9.898 million

TDF-HEC

Dr. Raheela Akhtar

TRAININGS / WORKSHOPS ORGANIZED:

Sr. No.

Title of Training / Workshop

No. of Participants

Event Dates

From

To

1

4th WPSA Technical workshop on Flock Health monitoring in poultry

More than 60

27 August 2019

27 August, 2019

2

2nd international workshop on basic mechanisms of disease and poultry pathology

100

2nd March, 2020

4th March, 2020

Faculty Development

  • Prof. Dr. Asim Aslam attended a two days “ International Seminar on Poultry Diseases” at University of Agriculture Faisalabad on 14-15 December 2015.
  • Prof. Dr. Asim Aslam attended the training program on “leadership and change management” held from 27­30th April, 2015 at IBA Karachi under the tertiary education support program of HEC.
  • Prof. Dr. Asim Aslam attended a two days workshop on “Small ruminant value change (SRVC)” under agriculture innovation program funded by USAID on 11­ 12th May held in Islamabad, 2015.

Co-curricular Activities

  • Study tour of undergraduate students to Slaughter house to examine and learn gross lesions of various diseases.
  • Annual dinner of department of Pathology arranged at Salt n pepper , Lahore
  • Post –Graduate study tour to A.W. Chicks Hatchery and Farms in District Kasur.

Invited Lectures

  1. Prof. Dr. Ashiq Hussain Cheema demonstrated  histopathological slides of various disease conditions.
  2. Dr. Asif Latif Manager Big Feed gave presentation on modern practices in broiler farming in controlled shed rearing system.
  3. Dr. Muhammad Raza Younus Manager Hi-Tech Feed delivered lectures on Poultry industry modernization and disease control strategies in Pakistan

Measures taken to Enhance the Academics

    1. Up-gradation of Labs & Lecture rooms.
    2. Thirteen latest Olympus microscopes added in under graduate Lab.
    3. Addition of Chemistry and hematology Analyzer in Hematology Lab.
    4. Renovation of incineration facility in the Postmortem block.

  Induction of Modern Equipment

    1. Fluorescent Microscopy & Image Analysis System.
    2. Establishment of Molecular Pathology Laboratory
    3. Establishment of Poultry Diagnostic Laboratory in Postmortem Teaching Block

Other Activity

Department of Pathology in collaboration with Higher Education Commission has organized three day workshop on “Recent Advances in Necropsy Practice in Livestock  and Poultry and its Vetro-Legal Implications” held on 25 to 27 Feb, 2015 at Conference Hall, UVAS, Lahore.

Research Priorities

  1. Development of advanced molecular diagnostic techniques for various infectious diseases
  2. Pathology and pathogenesis of various diseases of zoonotic importance
  3. Understanding the pathological mechanisms of infectious diseases caused by bacteria, viruses, parasites, and their vectors
  4. Developing novel approaches in the research of host-pathogen interaction and exploring its molecular pathogenesis for various infectious diseases.
  5. Studies on pathological effects of drugs/heavy metals/indigenous plants/ fungal toxins in animals and poultry
  6. Pathology and pathogenesis of infectious and non-infectious diseases of poultry
  7. Building bridge between basic research and in vivo application using animal models

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